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UPB:NASDAQ
Upstream Bio Inc
$6.01
-1.15%
(-0.070) 1D
$5.97
-0.67% (-0.040)
After hours
Closed: Sep 4, 4:00:00 PM GMT-4  ·   USD
All symbols
SymbolPriceChange% Change
Generating top insights for UPB...
Open
$6.00
High
$6.23
Low
$5.96
Mkt. cap
329.17M
Avg. vol.
620.15K
Volume
642.85K
52-wk high
$33.68
52-wk low
$5.77
EPS
-$2.89
Shares outstanding
54.77M
No. of employees
75
Open
$6.00
High
$6.23
Low
$5.96
Mkt. cap
329.17M
Avg. vol.
620.15K
Volume
642.85K
52-wk high
$33.68
52-wk low
$5.77
EPS
-$2.89
Shares outstanding
54.77M
No. of employees
75
News stories
From web sources and news partners
About Upstream Bio Inc
CEO-
Employees75
Founded2021
HeadquartersWaltham, Massachusetts, United States
SectorBiotechnology
Analyst ratings
Based on 6 analysts giving stock ratings to UPB in the past 3 months
Strong buy
Buy
5
Hold
1
Sell
0
12-month forecast
Based on 6 Wall Street analysts offering 12 month price targets for UPB in the last 3 months.
Highest
Current $6.01
$75.00 (+1,147.92%)
Average
$32.80 (+445.76%)
Lowest
$9.00 (+49.75%)
Analyst
Recommendation
Action
Price target
Projected
Date
Matthew Caufield
H.C. Wainwright
Buy
Reiterated
$36.00
+499%
09/02/2026
Kate Dellorusso
LifeSci Capital
Buy
Maintained
$19.00
+216.1%
09/01/2026
Matt Phipps
William Blair
Buy
Reiterated
-
-
09/01/2026
Tessa Romero
J.P. Morgan
Hold
Maintained
$9.00
+49.8%
08/14/2026
Danielle Brill
Truist Financial
Buy
Maintained
$25.00
+316%
08/12/2026
Yasmeen Rahimi
Piper Sandler
Buy
Maintained
$75.00
+1,147.9%
06/25/2026
Joseph Catanzaro
Mizuho Securities
Buy
Maintained
$50.00
+731.9%
05/14/2026
Yaron Werber
TD Cowen
Buy
Maintained
-
-
05/13/2026
Cory Kasimov
Evercore ISI
Hold
Downgraded
$15.00
+149.6%
03/27/2026
Last report
Aug 11, 2026
Fiscal period
Q2 2026
EPS / Est. (USD)
-$0.73 / -$0.76
+4.06%beat
Revenue / Est. (USD)
773.00K / 377.25K
+104.90%beat
Fiscal Q2 2026 earnings call
Waiting for the earnings call
At a glance
Insights from the latest news and reports
Previous reportsAll values in USD
Loading Previous Earnings...
Income statement
Revenue
Net income
All values in USD
Sep 2025
Dec 2025
Mar 2026
Jun 2026
Revenue
683.00K
668.00K
1.03M
773.00K
Cost of goods sold
-
-
-
-
Cost of revenue
-
-
-
-
Research and development expenses
32.98M
40.17M
36.56M
36.09M
Total research and development expenses
-
-
-
-
Selling, general, and admin expenses
5.54M
6.67M
8.08M
7.05M
Operating expense
38.52M
46.84M
44.65M
43.14M
Total operating expenses
38.52M
46.84M
44.65M
43.14M
Operating income
-37.83M
-46.17M
-43.62M
-42.37M
Other non operating income
-19.00K
54.00K
-30.00K
7.00K
EBT including unusual items
-33.75M
-42.46M
-40.59M
-39.70M
EBT excluding unusual items
-33.75M
-42.46M
-40.59M
-39.70M
Income tax expense
-
-
-
-
Effective tax rate
-
-
-
-
Other operating expenses
-
-
-
-
Net income
-33.75M
-42.46M
-40.59M
-39.70M
Net profit margin
-4,941.14%
-6,356.14%
-3,925.63%
-5,136.09%
Earnings per share
-0.63
-0.78
-0.75
-0.73
Interest and investment income
4.10M
3.65M
3.05M
2.66M
Interest expense
-
-
-
-
Net interest expenses
4.10M
3.65M
3.05M
2.66M
Depreciation and amortization charges
-
-
-
-
EBITDA
-37.79M
-46.11M
-43.57M
-42.32M
Gain or loss from assets sale
-
-
-
-
Insider transactions
Insider transactions data is drawn from third-party sources. Learn more
Insider
Position
Type
Date
Shares
Amount
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