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    Publication numberWO2006039685 A3
    Publication typeApplication
    Application numberPCT/US2005/035599
    Publication dateJan 4, 2007
    Filing dateOct 3, 2005
    Priority dateOct 1, 2004
    Also published asUS7247752, US20060088904, US20060088905, US20060111580, US20060155150, US20060167319, US20060178538, US20060183185, US20060183947, WO2006039685A2
    Publication numberPCT/2005/35599, PCT/US/2005/035599, PCT/US/2005/35599, PCT/US/5/035599, PCT/US/5/35599, PCT/US2005/035599, PCT/US2005/35599, PCT/US2005035599, PCT/US200535599, PCT/US5/035599, PCT/US5/35599, PCT/US5035599, PCT/US535599, WO 2006/039685 A3, WO 2006039685 A3, WO 2006039685A3, WO-A3-2006039685, WO2006/039685A3, WO2006039685 A3, WO2006039685A3
    InventorsSamuel F Lockwood, Peng Cho Tang, Geoff Nadolski, Zhiqiang Fang, Yishu Du, William Geiss, Richard Williams, William Burdick, Min Yang
    ApplicantHawaii Biotech Inc, Samuel F Lockwood, Peng Cho Tang, Geoff Nadolski, Zhiqiang Fang, Yishu Du, William Geiss, Richard Williams, William Burdick, Min Yang
    Export CitationBiBTeX, EndNote, RefMan
    Non-Patent Citations (13), Classifications (56), Legal Events (6)
    External Links: Patentscope, Espacenet
    Methods for synthesis of chiral intermediates of carotenoids, carotenoid analogs, and carotenoid derivatives
    WO 2006039685 A3
    Abstract
    A method used for synthesizing intermediates for use in the synthesis of carotenoids and carotenoid analogs, and/or carotenoid derivatives. In some embodiments, the invention includes methods for synthesizing optically active intermediates useful for the synthesis of optically active carotenoids.
    Non-Patent Citations
    Reference
    1 *D. LIOTTA ET AL.: "Pyridinium Dichromate-Induced 1,3-oxidative Rearrangements of Enynols", TETRAHEDRON LETT., vol. 28, no. 10, 1987, pages 1069 - 1072, XP002393247
    2 *DATABASE BEILSTEIN BEILSTEIN INSTITUTE FOR ORGANIC CHEMISTRY, FRANKFURT-MAIN, DE; XP002393250, Database accession no. Reaction ID 4538814
    3 *DATABASE BEILSTEIN BEILSTEIN INSTITUTE FOR ORGANIC CHEMISTRY, FRANKFURT-MAIN, DE; XP002393251, Database accession no. RN 3699622
    4 *HAUGAN J A ET AL: "TOTAL SYNTHESIS OF C31-METHYL KETONE APOCAROTENOIDS 3. ON THE STRUCTURE OF HOPKINSIAXANTHIN: FIRST TOTAL SYNTHESIS OF (ALL-E)-(3S)- AND (9Z)-(3S)-7'-APOHOPKINSIAXANTHIN", ACTA CHEMICA SCANDINAVICA, MUNKSGAARD, COPENHAGEN, DK, vol. 51, no. 12, 1997, pages 1201 - 1216, XP009063786, ISSN: 0904-213X
    5 *HENNIG M ET AL: "Synthesis of (R)- and (S)-4-hydroxyisophorone by ruthenium-catalyzed asymmetric transfer hydrogenation of ketoisophorone", TETRAHEDRON: ASYMMETRY, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 11, no. 9, May 2000 (2000-05-01), pages 1849 - 1858, XP004205809, ISSN: 0957-4166
    6 *KIENZLE F ET AL: "SYNTHESE VON OPTISCH AKTIVEN, NATUERLICHEN CAROTINOIDEN UND STRUKTURELL VERWANDTEN NATURPRODUKTEN. II. SYNTHESE VON (3S,3'S)-ASTAXANTHIN", HELVETICA CHIMICA ACTA, VERLAG HELVETICA CHIMICA ACTA. BASEL, CH, vol. 61, no. 7, 1978, pages 2609 - 2615, XP009048844, ISSN: 0018-019X
    7 *SRIKRISHNA ADUSUMILLI ET AL., J. CHEM. SOC. PERKIN TRANS 1, 11, 1996, pages 1305 - 1312
    8 *TAKAHASHI, SHUNYA ET AL., AGRIC. BIOL. CHEM., vol. 51, no. 4, 1987, pages 1143 - 1148
    9 *TANAKA A ET AL: "Lipase-Catalyzed Asymmetric Synthesis of (R)- and (S)-4-tert-Butyldimethylsilyloxy-2,6,6-trimethyl-2-cyclohexenone and Their Dihydro Derivatives", TETRAHEDRON: ASYMMETRY, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 6, no. 6, June 1995 (1995-06-01), pages 1273 - 1278, XP004048170, ISSN: 0957-4166
    10 *VON ARX, M. ET AL: "Unprecedented selectivity behavior in the hydrogenation of an .alpha.,.beta.-unsaturated ketone: hydrogenation of ketoisophorone over alumina-supported Pt and Pd", JOURNAL OF MOLECULAR CATALYSIS A: CHEMICAL, vol. 148, no. 1-2, 1999, pages 275 - 283, XP002374375
    11 *WIDMER E ET AL: "TECHNISCHE VERFAHREN ZUR SYNTHESE VON CAROTINOIDEN UND VERWANDTEN VERBINDUNGEN AUS 6-OXO-ISOPHORON. II. EIN NEUES KONZEPT FUER DIE SYNTHESE VON (3RS,3'RS)-ASTAXANTHIN", HELVETICA CHIMICA ACTA, VERLAG HELVETICA CHIMICA ACTA. BASEL, CH, vol. 64, no. 239, 1981, pages 2436 - 2446, XP009063882, ISSN: 0018-019X
    12 *WIDMER E ET AL: "TECHNISCHE VERFAHREN ZUR SYNTHESE VON CAROTINOIDEN UND VERWANDTEN VERBINDUNGEN AUS OXO-ISOPHORON. I. MODIFIZIERUNG DER KIENZLE-MAYER-SYNTHESE VON (3S,3'S)-ASTAXANTHIN", HELVETICA CHIMICA ACTA, VERLAG HELVETICA CHIMICA ACTA. BASEL, CH, vol. 64, no. 237, 1981, pages 2405 - 2418, XP009063877, ISSN: 0018-019X
    13 *ZELL R ET AL: "TECHNISCHE VERFAHREN ZUR SYNTHESE VON CAROTINOIDEN UND VERWANDTEN VERBINDUNGEN AUS 6-OXO-ISOPHORON. III. EIN NEUES KONZEPT FUER DIE SYNTHESE DER ENANTIOMEREN ASTAXANTHINE", HELVETICA CHIMICA ACTA, VERLAG HELVETICA CHIMICA ACTA. BASEL, CH, vol. 64, no. 7, 1981, pages 2447 - 2462, XP001202861, ISSN: 0018-019X
    * Cited by examiner
    Classifications
    International ClassificationC07F7/04, C07C45/65, C07C45/61, C07C45/74, C07C29/145, C07C47/21, C07C45/64, C07C33/14, C07C45/67, C07C45/29, C07C401/00, C07C49/713, C07C45/71, C07F7/18, C07C49/753
    Cooperative ClassificationC07C2601/16, C07C45/61, C07C49/753, C07C403/08, C07D319/06, C07B2200/07, C07C49/713, C07B2200/09, C07C403/24, C12P23/00, C07C47/21, C07C45/673, C07C45/70, C07F7/188, C07F7/1892, C07C45/71, C07F9/5442, C07C45/298, C07C45/64, C07F9/113, C07C45/511, C07C29/143
    European ClassificationC07F9/113, C07C45/29M, C07C45/67C, C07C45/71, C07C45/64, C07C45/70, C07C45/61, C07F9/54A4, C07C45/51B, C12P23/00, C07D319/06, C07C49/713, C07F7/18C9G, C07C49/753, C07C47/21, C07C29/143, C07F7/18C9B, C07C403/24, C07C403/08
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