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Facilitation de l'infection par des anticorps (Antibody-dependent enhancement)
La facilitation de l'infection par des anticorps est un phénomène se produisant lors d'une infection virale, quand des anticorps non neutralisants de l'hôte facilitent l'entrée du virus dans les cellules hôtes, et parfois aussi sa réplication. Wikipédia
9 sept. 2020 · One potential hurdle for antibody-based vaccines and therapeutics is the risk of exacerbating COVID-19 severity via antibody-dependent ...
13 juil. 2020 · Antibody-dependent enhancement (ADE) of disease is a general concern for the development of vaccines and antibody therapies because the ...
However, in some instances, the presence of specific antibodies can be beneficial to the virus. This activity is known as antibody-dependent enhancement ( …
PubMed/NCBI · How innate immune ... · 33888152
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What is ADE? ... ADE occurs when the antibodies generated during an immune response recognize and bind to a pathogen, but they are unable to prevent infection.
In antibody-dependent enhancement, DENV-specific antibody levels are too low to cover all the virion binding sites necessary for cell entry.
2 juil. 2021 · Antibody-dependent enhancement (ADE) is something researchers watch for very carefully and is extremely rare. In ADE, certain antibodies make it ...
The ADE of virus infection is a phenomenon in which virus-specific antibodies enhance the entry of virus, and in some cases the replication of virus, into ...
However, in some viruses, the binding of specific antibodies to viral surface proteins can promote viral invasion into certain types of cell instead, and ...
14 avr. 2020 · This immune backfiring, or so-called immune enhancement, may manifest in different ways such as antibody-dependent enhancement (ADE), ...
25 mai 2021 · Sometimes, after developing antibodies to a disease, our immune system can overreact the next time it gets exposed to the disease. This is a ...