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Here, we demonstrate that an anti-malaria drug, chloroquine, decreases the amount of an ... Keywords: ER stress; PLP; PMD; UPR; chloroquine; treatment.
9 juil. 2018 · Sunitinib combined with chloroquine reduces tumor growth through ... an important regulator of the UPR, through STF-083010 treatment in PDAC ...
This finding prompted us to examine the three major unfolded protein response (UPR) pathways (Yoshida et al. 2000, Ron & Walter 2007). In the MIN6 cells, ...
response (UPR) in glioma cells.20,35 Glioma cells protect. Chloroquine enhances temozolomide cytotoxicity in malignant gliomas by blocking autophagy.
24 mars 2020 · An Arizona man is dead and his wife was hospitalized after the couple ingested a form of chloroquine, ... UPR Utah Public Radio logo.
15 oct. 2018 · Inhibition of autophagy by chloroquine or genetic deletion of one ATG7 allele enhanced progression of mammary involution into the irreversible ...
8 juil. 2020 · US FDA approved hydroxychloroquine (HCQ) and chloroquine (CQ) for ... Autophagy and unfolded protein response (UPR) regulate mammary ...
The UPR is largely controlled by the activities of three pathways: PERK, IRE1a, ... The anti-malarial drugs chloroquine and hydroxychloroquine inhibit ...